Adenosine A(2A) agonists as therapy for glomerulonephritis.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 21799503.
- Also identified by DOI 10.1038/ki.2011.167.
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Abstract
Garcia et al. report the utility of pharmacological activation of the adenosine A(2A) receptor (A(2A)R) in preserving renal function, reversing fibrosis, and reducing macrophage infiltration and inflammatory activation in rat nephrotoxic nephritis. The role of A(2A)R activation in determining outcome in renal inflammation is discussed.
Medical subject headings
- Adenosine
- Adenosine A2 Receptor Agonists
- Anti-Inflammatory Agents
- Glomerulonephritis
- Kidney
- Phenethylamines
- Receptor, Adenosine A2A