The logic linking protein acetylation and metabolism.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 21803285.
- Also identified by DOI 10.1016/j.cmet.2011.07.007.
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Abstract
Protein acetylation now rivals phosphorylation in frequency of occurrence but is incompletely understood. A picture is presented in which protein acetylation is linked to available energy via the NAD-dependent deacetylases. This model suggests that protein acetylation regulates metabolic strategy and also helps store energy in cells.
Medical subject headings
- Histone Acetyltransferases
- Histone Deacetylases
- Proteins
- Sirtuins