Colistin-resistant, Klebsiella pneumoniae carbapenemase (KPC)-producing Klebsiella pneumoniae belonging to the international epidemic clone ST258.

Bogdanovich, Tatiana; Adams-Haduch, Jennifer M; Tian, Guo-Bao; Nguyen, Minh Hong; Kwak, Eun Jeong; Muto, Carlene A; Doi, Yohei · Clin Infect Dis · 2011

case_series · Level IV

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Abstract

Five cases of infection due to colistin-resistant, Klebsiella pneumoniae carbapenemase-producing K. pneumoniae belonging to the international epidemic clone ST258 occurred over a 4-month period. These cases likely represented both emergence of resistance and transmission of resistant organism. The colistin-resistant isolates were able to persist in the absence of selective pressure in vitro.

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