A simple code for installing hepatocyte function.
basic_science · Level V
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- Record sourced from PubMed, PMID 21816357.
- Also identified by DOI 10.1016/j.stem.2011.07.009.
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Abstract
Forced lineage conversion of accessible cell types can supply scarce or inaccessible cells for research and therapy. Two papers in Nature now report the identification of transcription factors sufficient for inducing therapeutically effective hepatocyte function in fibroblasts (Huang et al., 2011; Sekiya and Suzuki, 2011).