Gene editing in stem cells hits the target.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 21816359.
- Also identified by DOI 10.1016/j.stem.2011.07.011.
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Abstract
Two recent reports describe promising, highly efficient methods to modify genes in pluripotent stem cells using zinc finger nuclease (ZFN)-mediated (Soldner et al., 2011) or helper-dependent adenovirus (HDAdV)-mediated (Liu et al., 2011b) gene modification. These technical developments will have far ranging effects on the rapidly growing field of regenerative medicine.