Differentiating inherited human herpesvirus type 6 genome from primary human herpesvirus type 6 infection by means of dried blood spot from the newborn screening card.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 21840541.
- Also identified by DOI 10.1016/j.jpeds.2011.06.032.
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Abstract
To differentiate active human herpesvirus type 6 (HHV-6) infection from inherited HHV-6 (iHHV-6), we analyzed dried blood spots from archived newborn screening cards in 3 patients with high HHV-6 DNA copy numbers. Two patients were positive for HHV-6 DNA as neonates suggesting iHHV-6. In 1 patient, the absence of HHV-6 DNA excluded iHHV-6.
Medical subject headings
- Dried Blood Spot Testing
- Genome, Viral
- Herpesviridae Infections
- Herpesvirus 6, Human