ChimeraScan: a tool for identifying chimeric transcription in sequencing data.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 21840877.
- Also identified by DOI 10.1093/bioinformatics/btr467 and PMC identifier 3187648.
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Abstract
Next generation sequencing (NGS) technologies have enabled de novo gene fusion discovery that could reveal candidates with therapeutic significance in cancer. Here we present an open-source software package, ChimeraScan, for the discovery of chimeric transcription between two independent transcripts in high-throughput transcriptome sequencing data. http://chimerascan.googlecode.com cmaher@dom.wustl.edu Supplementary data are available at Bioinformatics online.
Medical subject headings
- Gene Fusion
- High-Throughput Nucleotide Sequencing
- Neoplasms
- Sequence Analysis, RNA
- Software