The osteoclast--what's new?
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 21847745.
- Also identified by DOI 10.1007/s00256-011-1180-9.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Bone resorption is required for skeletal modelling during bone growth and for mineral homeostasis and bone remodelling throughout life. Osteoclasts are multinucleated cells that are uniquely specialised to carry out this physiological bone resorption. As osteolysis is a feature of most diseases of bone and joint, osteoclasts also play a role in pathological bone resorption, the extent of which is a function of the cellular and molecular mechanisms that govern their formation and function.
Medical subject headings
- Bone Remodeling
- Bone Resorption
- Osteoclasts