JC virus antibody and viremia as predictors of progressive multifocal leukoencephalopathy in human immunodeficiency virus-1-infected individuals.
case_control · Level III
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- Record sourced from PubMed, PMID 21852452.
- Also identified by DOI 10.1093/cid/cir507 and PMC identifier 3166351.
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Abstract
We examined whether prediagnostic John Cunningham virus (JCV) antibodies and viremia are predictors of progressive multifocal leukoencephalopathy (PML) in 83 PML cases and 240 human immunodeficiency virus (HIV) disease-matched controls. JCV viremia was not predictive of PML, but some patients showed higher anti-JCV immunoglobulin G (IgG) responses 6 months prior to diagnosis.
Medical subject headings
- Antibodies, Viral
- HIV Infections
- HIV-1
- JC Virus
- Leukoencephalopathy, Progressive Multifocal
- Viremia