Osteosarcoma of the jaw in children and young adults.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 21853501.
- Also identified by DOI 10.1002/hed.21850.
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Abstract
Pediatric jaw osteosarcoma is uncommon, and data are scarce regarding clinical presentation, prognostic factors, and outcome. A single-institution medical record review from 1983 to 2008 for 12 patients age ≤ 21 years was undertaken for this study. Median diagnosis age was 16.3 years (range, 6.3-21.9). Nine patients had mandible tumors. Osteoblastic subtype was most common (4 patients). Most tumors were large (ie, T2; n = 8) and high-grade (n = 8). Treatment characteristics were varied. Median follow-up was 27.1 months (range, 8-252 months). Five patients had tumor necrosis <80% after chemotherapy. No deaths were observed. Jaw osteosarcoma outcome is better compared to extremity osteosarcoma, but further study is required regarding clinical prognostic factors.
Medical subject headings
- Jaw Neoplasms
- Osteosarcoma