Transcription factor loading: please take my place!
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 21854974.
- Also identified by DOI 10.1016/j.cell.2011.07.037.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Interactions of transcription factors with chromatin are highly dynamic. Now Voss et al. (2011) demonstrate that two transcription factors with identical DNA-binding specificities do not compete for occupancy at a given DNA element, but instead, one factor can even facilitate the binding of another. This assisted loading probably involves chromatin-remodeling machines.