Elongated membrane zones boost interactions of diffusing proteins.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 21854976.
- Also identified by DOI 10.1016/j.cell.2011.08.003.
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Abstract
Biological membranes are two dimensional, making the discovery of quasi-one-dimensional diffusion of membrane proteins puzzling. Jaqaman et al. (2011) now show that actomyosin and tubulin interact to establish long, thin diffusion corridors, thereby increasing the effective concentration of select membrane proteins to promote their interactions and modulate signaling.