The challenges of assessing acute kidney injury in infants.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 21878953.
- Also identified by DOI 10.1038/ki.2011.172.
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Abstract
Definitions of pediatric acute kidney injury (AKI) use changes of serum creatinine. There is a paucity of well-designed studies in infants because of creatinine age-dependency. The emerging role of cystatin C as a superior marker of renal dysfunction led to a carefully conducted study on AKI in infants by Zappitelli et al. This Commentary calls for the development of age-independent serum creatinine and estimated glomerular filtration rate z scores.
Medical subject headings
- Acute Kidney Injury
- Cardiac Surgical Procedures
- Cystatin C
- Postoperative Complications