Treatment of parainfluenza 3 infection with DAS181 in a patient after allogeneic stem cell transplantation.

Chen, Yi-Bin; Driscoll, Jessica P; McAfee, Steven L; Spitzer, Thomas R; Rosenberg, Eric S; Sanders, Rebecca; Moss, Ronald B; Fang, Fang et al. · Clin Infect Dis · 2011

case_report · Level V

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Abstract

Parainfluenza virus (PIV) can cause significant morbidity after allogeneic stem cell transplantation (SCT). We report the first use of inhaled DAS181 for PIV in an allogeneic SCT recipient. Symptoms, oxygenation, and pulmonary function tests improved. Nasopharyngeal samples showed a reduction in viral load. DAS181 should be systematically evaluated for severe PIV infection.

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