Osteolysis following resorbable poly-L-lactide-co-D, L-lactide PLIF cage use: a review of cases.

Abstract

Report of case series. To report a problem with bioabsorbable poly-L-lactide-co-D, L-lactide, PLDLLA, posterior lumbar instrumented fusion (PLIF) cage implants. Synthetic bioabsorbable implants have recently been introduced to spinal surgery and their indications and applications are still being explored. There is evidence that the use of bioabsorbable cages may be of benefit in interbody spinal fusion. We present a case series of nine patients who have undergone PLIF with bioabsorbable cages in the lumbar spine. At follow-up over at least 1 year, four of these patients were found to have osteolysis around the implant on CT scanning. One of these patients underwent an operation to remove the cage and histology sent during surgery suggested that the implant had caused the bone loss and there was no evidence of infection. Another patient had ongoing pain in relation to the lysis, while the other two patients with lysis remained asymptomatic. PLDLLA cage, which has high osteolytic nature, is considered not suitable as a fusion cage.