Basal synaptic transmission: astrocytes rule!
editorial · Level V
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- Record sourced from PubMed, PMID 21884929.
- Also identified by DOI 10.1016/j.cell.2011.08.006.
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Abstract
In this issue, Panatier et al. (2011) show that astrocytes detect synaptic activity induced by single action potentials and upregulate basal synaptic transmission through calcium-dependent mechanisms and purinergic signaling. These results demonstrate the relevance of astrocyte calcium in neurophysiology and confirm that astrocytes are actively involved in synaptic function.