A web of imprinting in stem cells.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 21885011.
- Also identified by DOI 10.1016/j.stem.2011.08.008.
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Abstract
Imprinted genes are the prototypical epigenetically regulated genes. On the basis of findings in adult lung stem cells, Zacharek et al. (2011) suggest in this issue of Cell Stem Cell that epigenetic silencing of imprinted genes is a common requirement for maintaining self-renewal in adult stem cell populations.
Medical subject headings
- Adult Stem Cells
- Cyclin-Dependent Kinase Inhibitor p16
- Gene Expression Regulation, Developmental
- Nuclear Proteins
- Proto-Oncogene Proteins
- Repressor Proteins
- S-Phase Kinase-Associated Proteins