Converting human skin cells to neurons: a new tool to study and treat brain disorders?
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 21885012.
- Also identified by DOI 10.1016/j.stem.2011.08.004.
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Abstract
Recent publications in Cell Stem Cell (Son et al., 2011; Ambasudhan et al., 2011), PNAS (Pfisterer et al., 2011), and Nature (Caiazzo et al., 2011; Pang et al., 2011; Yoo et al., 2011) report that functional neurons can be directly generated from human fibroblast cells without going through the pluripotent state.
Medical subject headings
- Electrical Synapses
- Fibroblasts
- Motor Neurons
- Spinal Cord
- Transcription Factors