Buspirone augmentation of fluoxetine in obsessive-compulsive disorder.

Markovitz, P J; Stagno, S J; Calabrese, J R · Am J Psychiatry · 1990

prospective_cohort · Level II

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Abstract

Eleven obsessive-compulsive patients underwent a prospective open-label trial of fluoxetine monotherapy followed by buspirone augmentation. The combination therapy was statistically superior to fluoxetine monotherapy. The results point to the importance of the 5-HT1a receptor in obsessive-compulsive disorder.

Medical subject headings