Understanding the enemy.
Level V
Where this comes from
- Record sourced from PubMed, PMID 21885403.
- Also identified by DOI 10.1126/scitranslmed.3003001 and PMC identifier 3652320.
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Abstract
In this issue of Science Translational Medicine, Tanas and colleagues describe a disease-defining genetic alteration for the vascular cancer epithelioid hemangioendothelioma (EHE). The resulting EHE-associated fusion gene encodes an aberrantly expressed putative transcription factor. This molecular information is the latest in a series of genetic discoveries that aid in cancer diagnosis and may pave the way to targeted therapeutic agents.
Medical subject headings
- Gene Fusion
- Hemangioendothelioma, Epithelioid