High-dose oral fluconazole therapy effective for cutaneous leishmaniasis due to Leishmania (Vianna) braziliensis.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 21890773.
- Also identified by DOI 10.1093/cid/cir496.
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Abstract
We report for the first time the successful use of fluconazole to treat cutaneous leishmaniasis due to Leishmania braziliensis. We used escalating doses from 5 to 8 mg/kg per day. At a dose of 5 mg/kg per day, 75% patients were cured, and at 8 mg/kg per day, the cure rate was 100%. Fluconazole was well tolerated.
Medical subject headings
- Antiprotozoal Agents
- Fluconazole
- Leishmania braziliensis
- Leishmaniasis, Cutaneous