Initial recovery and rebound of type f intestinal colonization botulism after administration of investigational heptavalent botulinum antitoxin.

Fagan, Ryan P; Neil, Karen P; Sasich, Randy; Luquez, Carolina; Asaad, Hakam; Maslanka, Susan; Khalil, Wajahat · Clin Infect Dis · 2011

case_report · Level V

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Abstract

Investigational heptavalent botulinum antitoxin (HBAT) is now the primary antitoxin for US noninfant botulism patients. HBAT consists of equine Fab/F(ab')2 IgG fragments, which are cleared from circulation faster than whole immunoglobulins. Rebound botulism after antitoxin administration is not previously documented but occurred in our patient 10 days after HBAT administration.

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