Molecular mechanism of protein folding in the cell.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 21907398.
- Also identified by DOI 10.1016/j.cell.2011.08.041.
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Abstract
F.-Ulrich Hartl and Arthur Horwich will share this year's Lasker Basic Medical Science Award for the discovery of the cell's protein-folding machinery, exemplified by cage-like structures that convert newly synthesized proteins into their biologically active forms. Their fundamental findings reveal mechanisms that operate in normal physiologic processes and help to explain the problems that arise in diseases of protein folding.
Medical subject headings
- Awards and Prizes
- Biology
- Protein Folding
- Proteins