Multicentric reticulohistiocytosis. Detailed immunophenotyping confirms macrophage origin.
case_report · Level V
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Abstract
A case study of multicentric reticulohistiocytosis is presented with extensive immunohistochemical studies of the infiltrate in both paraffin and cryostat sections. These studies showed that the cells are of monocyte/macrophage origin. B- and T-cell gene rearrangement analysis of multicentric reticulohistiocytosis was also performed and showed a germline configuration.
Medical subject headings
- Histiocytosis, Non-Langerhans-Cell
- Macrophages