Using elastic light scattering of red blood cells to detect infection of malaria parasite.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 21926010.
- Also identified by DOI 10.1109/TBME.2011.2168398.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
To develop noninvasive diagnosis of malaria, we studied the light-scattering pattern of healthy and 2% Plasmodium falciparum malaria parasitized red blood cells. By measuring the wavelength-dependent scattering at discrete angles of both forward and backward directions, we found that the signal can clearly distinguish between healthy and ring stage infected red blood cells. In particular, we demonstrated the first backward scattering measurement, which enables elastic light scattering as a promising noninvasive diagnostic tool for malaria.
Medical subject headings
- Diagnosis, Computer-Assisted
- Erythrocytes
- Malaria
- Nephelometry and Turbidimetry
- Plasmodium falciparum
- Refractometry