Clinical manifestations of HIV infection, including persistent generalized lymphadenopathy and AIDS-related complex.

Abstract

The ability to recognize disease related to the human immunodeficiency virus (HIV) and subsequent acquired immunodeficiency syndrome (AIDS) has improved in recent years with refinement of laboratory techniques. Because of this progress, several clinical conditions can now be identified as "pre-AIDS" syndromes. These include the persistent generalized lymphadenopathy syndrome, immune thrombocytopenic purpura, the wasting syndrome, and certain predominantly neurologic presentations. All are characterized by the presence of infection with HIV, symptomatic disease, and, over time, an increasing tendency to progress to "full-blown" AIDS.