Radiologic appearance of hereditary adrenal and extraadrenal paraganglioma.

Ingram, Mark; Barber, Brendan; Bano, Gul; Patel, Uday; Vlahos, Ioannis · AJR Am J Roentgenol · 2011

review · Level V

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Abstract

There is a wide spectrum of established and emerging genetic mutations associated with intraadrenal and extraadrenal paragangliomas. In this review, we present the typical radiologic patterns of disease associated with six well-characterized genetic mutations and discuss other inherited and nonfamilial syndromes currently under characterization. Contrary to previous understanding, recent genotype advances suggest that the majority of paragangliomas may be genetically predisposed.

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