Genetics of lumbar disk degeneration: technology, study designs, and risk factors.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 21944585.
- Also identified by DOI 10.1016/j.ocl.2011.07.011.
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Abstract
Lumbar disk degeneration (LDD) is a common musculoskeletal condition. Genetic risk factors have been suggested to play a major role in its cause. This article reviews the main research strategies that have been used to study the genetics of LDD, and the genes that thus far have been identified to influence susceptibility to LDD. With the rapid progress in genomic technologies, further advances in the genetics of LDD are expected in the next few years.
Medical subject headings
- Genetic Predisposition to Disease
- Genomics
- Intervertebral Disc Degeneration
- Low Back Pain
- Lumbar Vertebrae
Anatomy
- lumbar spine