Shape-memory surface with dynamically tunable nano-geometry activated by body heat.

Ebara, Mitsuhiro; Uto, Koichiro; Idota, Naokazu; Hoffman, John M; Aoyagi, Takao · Adv Mater · 2012

basic_science · Level V

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Abstract

Shape-memory surfaces with on-demand, tunable nanopatterns are developed to observe time dependent changes in cell alignment using temperature-responsive poly(ϵ-caprolactone) (PCL) films. Temporary grooved nanopatterns are easily programmed on the films and triggered to transition quickly to permanent surface patterns by the application of body heat. A time-dependent cytoskeleton remodeling is also observed under biologically relevant conditions.

Medical subject headings