Splicing up pluripotency.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 21962502.
- Also identified by DOI 10.1016/j.cell.2011.09.004.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
In this issue of Cell, Gabut and colleagues (2011) identify a new splice variant of FOXP1 that directly regulates the expression of pluripotency genes. It endows human embryonic stem cells with their pluripotent nature and is required for the reprogramming of somatic cells to induced pluripotent stem cells.