ProfileChaser: searching microarray repositories based on genome-wide patterns of differential expression.

Engreitz, Jesse M; Chen, Rong; Morgan, Alexander A; Dudley, Joel T; Mallelwar, Rohan; Butte, Atul J · Bioinformatics · 2011

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Abstract

We introduce ProfileChaser, a web server that allows for querying the Gene Expression Omnibus based on genome-wide patterns of differential expression. Using a novel, content-based approach, ProfileChaser retrieves expression profiles that match the differentially regulated transcriptional programs in a user-supplied experiment. This analysis identifies statistical links to similar expression experiments from the vast array of publicly available data on diseases, drugs, phenotypes and other experimental conditions. http://profilechaser.stanford.edu abutte@stanford.edu Supplementary data are available at Bioinformatics online.

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