Ceftriaxone-induced hemolysis in a child with Lyme arthritis: a case for antimicrobial stewardship.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 21969285.
- Also identified by DOI 10.1542/peds.2010-1570.
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Abstract
Guidelines for the treatment of Lyme arthritis were published by the Infectious Diseases Society of America in 2006 and recommended oral doxycycline for initial therapy. We report here the case of a young girl treated with intravenous ceftriaxone who subsequently developed drug-induced autoimmune hemolytic anemia and renal failure. Her severe sequelae highlight the importance of antimicrobial stewardship. We review here the goals of antimicrobial stewardship and several strategies for achieving them. In addition, we briefly discuss the rare adverse drug event experienced by our patient.
Medical subject headings
- Acute Kidney Injury
- Anemia, Hemolytic
- Anti-Bacterial Agents
- Ceftriaxone
- Kidney Cortex Necrosis
- Lyme Disease