Transistor-like behavior of single metalloprotein junctions.

Artés, Juan M; Díez-Pérez, Ismael; Gorostiza, Pau · Nano Lett · 2012

basic_science · Level V

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Abstract

Single protein junctions consisting of azurin bridged between a gold substrate and the probe of an electrochemical tunneling microscope (ECSTM) have been obtained by two independent methods that allowed statistical analysis over a large number of measured junctions. Conductance measurements yield (7.3 ± 1.5) × 10(-6)G(0) in agreement with reported estimates using other techniques. Redox gating of the protein with an on/off ratio of 20 was demonstrated and constitutes a proof-of-principle of a single redox protein field-effect transistor.

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