Striking a balance between feasible and realistic biological models.

Califano, Andrea · Sci Transl Med · 2011

basic_science · Level V

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Abstract

The fusion of empirical science with large-scale computing platforms has allowed rapid advances in our ability to model physiological and pathophysiological processes in silico. In this week's issue of Science Translational Medicine, Tran et al. present a simple framework for the quantitative modeling of oncogene addiction that provides mechanistic insights into tumor biology.

Medical subject headings