Long live sox2: sox2 lasts a lifetime.
editorial · Level V
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- Record sourced from PubMed, PMID 21982223.
- Also identified by DOI 10.1016/j.stem.2011.09.007.
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Abstract
Sox2 is a key transcription factor required for the maintenance of pluripotency in embryonic cells and morphogenesis of several epithelia. In this issue of Cell Stem Cell, Arnold et al. (2011) demonstrate that Sox2 marks long-lived adult stem cells to ensure homeostasis in a broad range of adult tissues.