Orexin turns up the heat on obesity.

Seale, Patrick · Cell Metab · 2011

basic_science · Level V

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Abstract

Brown adipocytes burn chemical energy to produce heat for protection against hypothermia and obesity. Sellayah et al. now reveal that a secreted neuropeptide, Orexin, functions a key driver of brown adipocyte differentiation through direct actions on brown adipose precursors.