Posaconazole for chronic refractory coccidioidal meningitis.

Schein, Rebecca; Homans, James; Larsen, Robert A; Neely, Michael · Clin Infect Dis · 2011

case_series · Level IV

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Abstract

Coccidioidal meningitis is a potentially lethal infection. Disease progression while taking fluconazole is a common complication and safe, effective, alternative treatments are limited. Posaconazole therapy resulted in symptomatic and laboratory improvement in 2 patients and clinical improvement in a third patient with chronic, previously unresponsive coccidioidal meningitis.

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