Novel use of prasugrel for intracranial stent thrombosis.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 21990454.
- Also identified by DOI 10.1136/jnis.2010.004382.
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Abstract
Dual antiplatelet therapy is established for prevention of stent thrombosis in cardiac patients, and widely utilized in neurointerventional stent cases. Aspirin and clopidogrel are typically synergistic. We present a case of clopidogrel resistance due to genetic polymorphism resulting in acute stent thrombosis during elective stent-assisted coiling, with novel use of prasugrel as an alternative platelet inhibitor in the neurovascular setting.
Medical subject headings
- Intracranial Thrombosis
- Piperazines
- Platelet Aggregation Inhibitors
- Stents
- Thiophenes