Ultrasensitive diagnosis for an anthrax-protective antigen based on a polyvalent directed peptide polymer coupled to zinc oxide nanorods.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 21997757.
- Also identified by DOI 10.1002/adma.201103284.
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Abstract
A flexible poly-D-lysine polymer conjugated with different target-binding peptides is demonstrated with an ultralow concentration detection limit compared to those of other conventional detection systems. This polyvalent directed peptide polymer (PDPP) exhibits increased binding affinity and detects anthrax protective antigen at low levels using a well-known zinc oxide nanorod detection system.
Medical subject headings
- Antigens, Bacterial
- Bacterial Toxins
- Biosensing Techniques
- Nanotubes
- Peptides
- Zinc Oxide