Micromanaging the classification of colon cancer: the role of the microRNAome.
Level V
Where this comes from
- Record sourced from PubMed, PMID 22019515.
- Also identified by DOI 10.1158/1078-0432.CCR-11-2440 and PMC identifier 3422018.
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Abstract
Recent advances in our understanding of the microRNAome (miRNAome) have provided further insights into the molecular pathogenesis of colorectal cancer and shown a potential role for miRNAs in distinguishing molecular subtypes. The mucosa-adenoma-carcinoma model can now integrate miRNAs into the known genetic alterations that drive the progression of colorectal neoplasia.
Medical subject headings
- Adenocarcinoma
- Adenoma
- Colorectal Neoplasms
- MicroRNAs
- Microsatellite Instability
- Microsatellite Repeats
- Protein Array Analysis