Setting the tone: reactive oxygen species and the control of appetitive melanocortin neurons.
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- Record sourced from PubMed, PMID 22055500.
- Also identified by DOI 10.1016/j.cmet.2011.10.004.
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Abstract
The brain melanocortin system is a primary gateway through which energy balance is controlled. Diano and colleagues report a novel cellular mechanism mediated via reactive oxygen species (ROS) that regulates the activity of these melanocortin neurons in response to energy status, thereby modulating appetitive behavior (Diano et al., 2011).