Shrink-film configurable multiscale wrinkles for functional alignment of human embryonic stem cells and their cardiac derivatives.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 22065428.
- Also identified by DOI 10.1002/adma.201103463.
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Abstract
A biomimetic substrate for cell-culture is fabricated by plasma treatment of a prestressed thermoplastic shrink film to create tunable multiscaled alignment "wrinkles". Using this substrate, the functional alignment of human embryonic stem cell derived cardiomyocytes is demonstrated.
Medical subject headings
- Embryonic Stem Cells
- Myocardium
- Myocytes, Cardiac