Old friends form alliance against podocytes.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 22083635.
- Also identified by DOI 10.1038/ki.2011.298.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Wang and colleagues identify the activation of Wnt signaling as an important downstream event in transforming growth factor-β-mediated podocyte injury. Supported by other recent studies, canonical Wnt signaling is emerging as a critical stress pathway in podocytes and may be exploited for therapeutic strategies in the treatment of glomerulopathies.
Medical subject headings
- Podocytes
- Proteinuria
- Transforming Growth Factor beta1
- Wnt Proteins
- Wnt Signaling Pathway
- beta Catenin