Chiral nanoporous metal-organic frameworks with high porosity as materials for drug delivery.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 22095878.
- Also identified by DOI 10.1002/adma.201102538.
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Abstract
A chiral nanoporous metal-organic framework (MOF) with high porosity is obtained based on nontoxic zinc and achiral hexadentate ligand. It shows high drug loading and slow release of the proportion of the loaded drug with a complete delivery time of about one week when used as a material for adsorption and delivery of anticancer 5-fluorouracil.
Medical subject headings
- Drug Carriers
- Nanostructures
- Organometallic Compounds