Decreased expression of acetaminophen-metabolizing enzymes and glutathione in asthmatic children after acetaminophen exposure.

Stephenson, Susan T; Hadley, Graham; Brown, Lou Ann S; Fitzpatrick, Anne M · J Allergy Clin Immunol · 2012

Level V

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Abstract

Children with moderate-to-severe asthma have decreased expression of acetaminophen metabolizing genes and glutathione that may account for the previously-reported risk of acetaminophen in this vulnerable population.

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