Seeing the light: probing ROS in vivo using redox GFP.
basic_science · Level V
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- Record sourced from PubMed, PMID 22152299.
- Also identified by DOI 10.1016/j.cmet.2011.11.008.
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Abstract
Reactive oxygen species (ROS) dictate biological outcomes and are linked with myriad pathologies. However, measuring ROS in vivo remains a major obstacle in the field. Here, Albrecht et al. (2011) demonstrate the efficacy of redox-sensitive GFP in measuring glutathione redox state and H(2)O(2) levels of tissues in Drosophila.