Weaving the web of ER tubules.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 22153070.
- Also identified by DOI 10.1016/j.cell.2011.11.022 and PMC identifier 3478066.
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Abstract
How is the characteristic shape of an organelle generated? Recent work has provided insight into how the tubular network of the endoplasmic reticulum (ER) is formed. The tubules themselves are shaped by the reticulons and DP1/Yop1p, whereas their fusion into a network is brought about by membrane-bound GTPases that include the atlastins, Sey1p, and RHD3.
Medical subject headings
- Endoplasmic Reticulum