Effect of plasmapheresis on serum and CSF autoantibody levels in CNS paraneoplastic syndromes.

Graus, F; Abos, J; Roquer, J; Mazzara, R; Pereira, A · Neurology · 1990

case_series · Level IV

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Abstract

We compared the effect of plasmapheresis on antineuronal autoantibody titers in the serum and CSF of 3 patients with CNS paraneoplastic syndromes. Plasmapheresis reduced the serum autoantibody titer to 20% of the initial levels in the 3 patients, but the CSF autoantibody titer decreased only in the patient with severe damage of the blood-brain barrier.

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