Pulmonary infiltrates and fever induced by isoniazid.

Salomaa, E R; Ruokonen, E L; Tevola, K; Tala, E · Postgrad Med J · 1990

case_report · Level V

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Abstract

An 88 year old woman with bacteriologically confirmed pulmonary tuberculosis was first treated with isoniazid, rifampicin and pyrazinamide. Two weeks later she developed pulmonary infiltrates with fever. A drug-induced reaction was suspected but the reaction recurred three times until isoniazid was identified as the cause. The reaction became worse each time, finally being nearly fatal.

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