Maleimide cross-linked bioactive PEG hydrogel exhibits improved reaction kinetics and cross-linking for cell encapsulation and in situ delivery.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 22174081.
- Also identified by DOI 10.1002/adma.201103574 and PMC identifier 3517145.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Engineered polyethylene glycol-maleimide matrices for regenerative medicine exhibit improved reaction efficiency and wider range of Young’s moduli by utilizing maleimide cross-linking chemistry. This hydrogel chemistry is advantageous for cell delivery due to the mild reaction that occurs rapidly enough for in situ delivery, while easily lending itself to “plug-and-play” design variations such as incorporation of enzyme-cleavable cross-links and cell-adhesion peptides.
Medical subject headings
- Cross-Linking Reagents
- Hydrogel, Polyethylene Glycol Dimethacrylate
- Maleimides
- Polyethylene Glycols